The special technology that created Novasuede allows for easy care and cleaning. Since liquid spills tend to "bead up" on the surface, often all that is needed is quick action with a dry cloth to absorb the liquid. Normal, regular vacuuming with a soft brush attachment is recommended to remove dust deposits, prevent soil build-up, and to keep the suede surface looking crisp and new. Light stains and smudge marks often can be lifted off with Scotch tape or removed with a soft eraser.

Water soluble stains such as coffee, tea, juice, soft drinks, milk, beer, wine, etc. can be removed by dabbing the affected area with clean water only, mild soapy water, or a 50/50 solution of water and white vinegar. Excessive rubbing is not necessary. A blotting action is always preferable to a rubbing technique for stain removal. Remove excess soap or vinegar solution by dabbing again with clean water and blotting with a clean cloth. The material can be allowed to dry naturally or dried quickly with a hair dryer using the warm setting. "Rings" noticed after drying are usually the result of some residual soap or cleaning solution remaining in the fabric. Most rings can be removed by cleaning again with water only.

For non-water soluble stains such as grease, oil, shoe polish, etc. use a petroleum solvent such as naphtha (lighter fluid) or mineral spirits.  Using a clean cloth moistened with the solvent, dab the stained area and then blot with a clean, dry cloth. Repeat if necessary. Work from the edges of the stain toward the center to avoid enlarging the stain. Surface damage and minor cigarette burns usually can be repaired by rubbing the area carefully with fine sandpaper.

Removable covers can be machine washed separately using the cool or warm water setting, delicate cycle. Use mild detergent, no bleach. Do not pour detergent directly onto the material. Spin and tumble dry low setting, or spin and hang to dry in a shady area. Do not twist or wring. Novasuede covers can also be professionally dry cleaned using clean perchloroethylene solvent, short cycle, tumble dry warm, steam only followed by brushing to restore nap.

To clean widespread dirt or overall cleaning of upholstered pieces, a wet extraction process is recommended, available through most professional cleaning services.

Although Novasuede is spill resistant, supplementary treatments such as Scotchguard can be used. Preliminary sample treatment is necessary to ensure that the hand, texture, or color of the material will not be affected.

After any method of cleaning, it is important to restore the nap by light brushing with a soft bristle brush after the Novasuede is completely dry. Regular routine vacuuming, immediate attention to accidental spills, and occasional brushing is generally all that is required to maintain the luxurious feel and appearance of Novasuede.